Risk evaluation of circulating Middle East respiratory syndrome coronavirus (MERS-CoV) clades and lineages

Overview

Updated: 19 November 2025

This document summarizes discussions during a Technical Advisory Group on Virus Evolution (TAG-VE) meeting held on 2 June 2025, and reviews current evidence from the global genomic surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) to highlight gaps in existing knowledge, proposes recommendations for further studies, and focus on better understanding the genetic diversity associated with this zoonotic virus.